P-methylbenzene sulfonyl methyl isonitrile

? English Name: p-toluenesulfonyl methyl isocyanide; Tosmic; Tosyl Methyl Isocyanide

? Alias: p-toluenesulfonylmethylcarbamide; P-tolyl isohydric acid ester; 4-toluenesulfonyl carbamide; P-methylsulfonyl methyl isonitrile; P-toluenesulfonyl methyl isonitrile; P-toluenesulfonyl methyl isocyanide; P-methylbenzene sulfonyl methyl isonitrile; Bis Toluenesulfonyl methyl isocyanide; 1h-indazole-14-ol; P-sulfonyltoluene methylisonitrile.

? Content: ≥ 99.5%

? CAS No.: 36635-61-7

? Molecular formula: ch3c6h4so2ch2nc

? Molecular weight: 195.24

? Melting point: 109-113 ℃

? Appearance: yellow to brown crystal

? Sensitivity: moisture absorption

? Storage conditions: sensitive to moisture, dry storage.

Product introduction

? 1,5-disubstituted imidazole was obtained by base promoted 1,3-dipolar cycloaddition reaction of p-toluenesulfonyl methylisonitrile with immobilized imine under microwave radiation. It is a multifunctional synthon in organic chemistry and is widely used in the synthesis of heterocyclic compounds.

 

Purpose

P-methylbenzene sulfonyl methyl isonitrile:

? used in the synthesis of triad drugs with 1,3,5-trioxyheterocyclohexane skeleton

? used as a reagent for the preparation of bioactive pyrrole and imidazole

? used as an isonitrile component in diastereoselective passerine reactions using sugar derived aldehydes

 

Packing

20kg square paper bucket; 25kg round paper bucket